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Synonyms: TMPY-04343, TMPY-00676, Programmed Death Ligand 1, Programmed death ligand 1, Programmed cell death ligand 1, Programmed Cell Death 1 Ligand 1, PD-L1B7 homolog 1, PDL-1, PD-L1, PDL1, PDL 1, PDCD1LG1, PDCD1L1, PDCD1 ligand 1, PDCD1 Ligand 1, hPD-L1, CD274 molecule, CD-274, CD274, CD 274, B7-H1, B7H1, B7-H, B7 Homolog 1, B7 homolog 1


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human PD-L1, LIama Fc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Human PD-1, mFc Tag with the EC50 of 0.17 μg/ml determined by ELISA. |
| Description | PD-L1 Protein, Human, Recombinant (LlaFc) is expressed in HEK293 Cells. The accession number is Q9NZQ7-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-Llama Fc |
| Accession Number | Q9NZQ7-1 |
| Construction | Phe19-Arg238 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TMPY-04343, TMPY-00676, Programmed Death Ligand 1, Programmed death ligand 1, Programmed cell death ligand 1, Programmed Cell Death 1 Ligand 1, PD-L1B7 homolog 1, PDL-1, PD-L1, PDL1, PDL 1, PDCD1LG1, PDCD1L1, PDCD1 ligand 1, PDCD1 Ligand 1, hPD-L1, CD274 molecule, CD-274, CD274, CD 274, B7-H1, B7H1, B7-H, B7 Homolog 1, B7 homolog 1 |
| Research Background | B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. |
| Molecular Weight | 52.50 kDa (Predicted); 65-75 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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