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Anti-BRMS1 Antibody (4O811)

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Catalog No. TMAB-03222

Anti-BRMS1 Antibody (4O811) is a Rabbit antibody targeting BRMS1. Anti-BRMS1 Antibody (4O811) can be used in ICC/IF, IF, IHC-Fr, IHC-P.

Anti-BRMS1 Antibody (4O811)

Anti-BRMS1 Antibody (4O811)

😃Good
Catalog No. TMAB-03222
Anti-BRMS1 Antibody (4O811) is a Rabbit antibody targeting BRMS1. Anti-BRMS1 Antibody (4O811) can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-BRMS1 Antibody (4O811) is a Rabbit antibody targeting BRMS1. Anti-BRMS1 Antibody (4O811) can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Ig Type
IgG
Clone
4O811
Reactivity
Human
Application
Recommended Dose
ICC/IF=1:50-200; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Predominantly nuclear.
Tissue SpecificityExpression levels are higher in term placentas than in early placentas. Low levels of expression observed in normal pregnancies and in molar pregnancies.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Antigen Details
Immunogen
A synthesized peptide: human BRMS1
Antigen Species
Human
Gene Name
BRMS1
Gene ID
Protein Name
Breast cancer metastasis-suppressor 1
Uniprot ID
Function
Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.
Chemical Properties
Molecular WeightTheoretical: 28 kDa. Actual: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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