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TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc)
(Synonyms: TIMD-3, TIMD3, TIMD 3, TIM-3, Tim-3, TIM3, TIM 3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3, KIM-3, KIM3, KIM 3, hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, HAVCR-2, HAVCR2, HAVCR 2, FLJ-14428, FLJ14428, FLJ 14428, CD-366, CD366, CD 366, FLJ14428) Copy Product InfoSynonyms: TIMD-3, TIMD3, TIMD 3, TIM-3, Tim-3, TIM3, TIM 3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3, KIM-3, KIM3, KIM 3, hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, HAVCR-2, HAVCR2, HAVCR 2, FLJ-14428, FLJ14428, FLJ 14428, CD-366, CD366, CD 366, FLJ14428
Catalog No. TMPK-02023 Copy Product Info
TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc) is expressed in HEK293 Cells. The accession number is Q8TDQ0-1.
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $81 | 7-10 days | 7-10 days | |
| 10 µg | $123 | 7-10 days | 7-10 days | |
| 20 µg | $193 | 7-10 days | 7-10 days | |
| 50 µg | $348 | 7-10 days | 7-10 days | |
| 100 µg | $553 | 7-10 days | 7-10 days | |
| 200 µg | $878 | 7-10 days | 7-10 days | |
| 500 µg | $1,630 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Human TIM-3, LIama Fc Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-TIM-3 Antibody, hFc Tag with the EC50 of 0.14 μg/ml determined by ELISA (QC Test). |
| Description | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc) is expressed in HEK293 Cells. The accession number is Q8TDQ0-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-Llama Fc |
| Accession Number | Q8TDQ0-1 |
| Construction | Ser22-Arg200 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE |
| Endotoxin | < 0.1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | TIMD-3, TIMD3, TIMD 3, TIM-3, Tim-3, TIM3, TIM 3, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, T-cell immunoglobulin and mucin domain-containing protein 3, KIM-3, KIM3, KIM 3, hepatitis A virus cellular receptor 2, Hepatitis A virus cellular receptor 2, HAVcr-2, HAVCR-2, HAVCR2, HAVCR 2, FLJ-14428, FLJ14428, FLJ 14428, CD-366, CD366, CD 366, FLJ14428 |
| Research Background | Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. |
| Molecular Weight | 47.18 kDa (Predicted); 70-90 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc) chemical structure | TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (LlaFc) molecular weight
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