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Anti-Adiponectin Antibody (3M155)

🥰Excellent
Catalog No. TMAB-02343

Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IHC-P,IHC-Fr,ICC/IF,IF
Reactivity: Mouse

Anti-Adiponectin Antibody (3M155)

Anti-Adiponectin Antibody (3M155)

🥰Excellent
Catalog No. TMAB-02343
Antibody Type: Recombinant Rabbit Monoclonal
Application: WB,IHC-P,IHC-Fr,ICC/IF,IF
Reactivity: Mouse
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Product Introduction

Bioactivity
Description
Anti-Adiponectin Antibody (3M155) is a Rabbit antibody targeting Adiponectin. Anti-Adiponectin Antibody (3M155) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Clone
3M155
Reactivity
Mouse
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
Tissue SpecificitySynthesized exclusively by adipocytes and secreted into plasma.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundImportant adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion.
Antigen Details
Immunogen
A synthesized peptide: mouse Adiponectin
Antigen Species
Mouse
Gene Name
ADIPOQ
Gene ID
Protein Name
Adiponectin
Uniprot ID
Function
Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Chemical Properties
Molecular WeightTheoretical: 27 kDa. Actual: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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