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Anti-Lamin B Receptor Antibody (4J688) is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Antibody (4J688) can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
| Description | Anti-Lamin B Receptor Antibody (4J688) is a Rabbit antibody targeting Lamin B Receptor. Anti-Lamin B Receptor Antibody (4J688) can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Clone | 4J688 |
| Reactivity | Human,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus inner membrane; Multi-pass membrane protein. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation .Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation.Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| Immunogen | A synthesized peptide: human Lamin B Receptor |
| Antigen Species | Human |
| Gene Name | LBR |
| Gene ID | |
| Protein Name | delta(14)-sterol reductase LBR |
| Uniprot ID | |
| Function | Anchors the lamina and the heterochromatin to the inner nuclear membrane. |
| Molecular Weight | Theoretical: 71 kDa. Actual: 70 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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