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Anti-COX-2 Antibody (4N211)
😃Good
Catalog No. TMAC-00948
Alias prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2
Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB.
Anti-COX-2 Antibody (4N211)
Anti-COX-2 Antibody (4N211)
😃Good
Catalog No. TMAC-00948Alias prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2
Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB. |
| Synonyms | prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2 |
| Ig Type | IgG |
| Clone | 4N211 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of COX2 on different lysates using anti-COX2 antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: THP-1. 2. ICC staining COX2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining COX2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining COX2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.     |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general ??housekeeping?? functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic inflammatory drugs, NSAIDs. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 72 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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