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Anti-COX-2 Antibody (4N211) (Synonyms: prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2|...)

Catalog No. TMAC-00948 Copy Product Info
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Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB.

Anti-COX-2 Antibody (4N211)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00948
Synonyms prostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2

Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB.

Anti-COX-2 Antibody
(4N211)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-COX-2 Antibody (4N211) is a Rabbit antibody targeting COX-2. Anti-COX-2 Antibody (4N211) can be used in ICC/IF,WB.
Synonymsprostaglandin-endoperoxide synthase 2, PHS-2, PGHS-2, PGG/HS, hCox-2, GRIPGHS, COX-2, COX2
Ig Type
IgG
Clone
4N211
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of COX2 on different lysates using anti-COX2 antibody at 1/1,000 dilution. Positive control: Lane 1: A549, Lane 2: THP-1.
2. ICC staining COX2 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining COX2 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining COX2 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundProstaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general ??housekeeping?? functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic inflammatory drugs, NSAIDs.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 72 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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