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Anti-NGF Antibody (6U823)
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Catalog No. TMAH-00817
Alias β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF
Anti-NGF Antibody (6U823) is an antibody targeting NGF. Anti-NGF Antibody (6U823) can be used in ELISA, FC.
Anti-NGF Antibody (6U823)
Anti-NGF Antibody (6U823)
😃Good
Catalog No. TMAH-00817Alias β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF
Anti-NGF Antibody (6U823) is an antibody targeting NGF. Anti-NGF Antibody (6U823) can be used in ELISA, FC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $207 | 7-10 days | |
| 100 μL | $349 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-NGF Antibody (6U823) is an antibody targeting NGF. Anti-NGF Antibody (6U823) can be used in ELISA, FC. |
| Alias | β-NGF, NGFB, nerve growth factor (β polypeptide), nerve growth factor (beta polypeptide), HSAN5, Beta-NGF |
| Ig Type | hIgG2 |
| Clone | 6U823 |
| Reactivity | Human |
| Verified Activity | Overlay Peak curve showing PC3 cells stained with TMAH-00817 (red line) at 1:100. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-human IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was human IgG (1ug/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| Application | ELISA, FC |
| Recommended Dose | FC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Secreted. Endosome lumen. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival (Probable). The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human NGF Protein |
| Antigen Species | Human |
| Gene ID | 4803 |
| Uniprot ID | |
| Biology Area | Neuroscience |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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