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Anti-PCGF4/BMI1 Antibody (1L149)

Catalog No. TMAB-10066 Copy Product Info
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Anti-PCGF4/BMI1 Antibody (1L149) is a Rabbit antibody targeting PCGF4/BMI1. Anti-PCGF4/BMI1 Antibody (1L149) can be used in WB.

Anti-PCGF4/BMI1 Antibody (1L149)

Copy Product Info
🥰Excellent
Catalog No. TMAB-10066

Anti-PCGF4/BMI1 Antibody (1L149) is a Rabbit antibody targeting PCGF4/BMI1. Anti-PCGF4/BMI1 Antibody (1L149) can be used in WB.

Anti-PCGF4/BMI1 Antibody
(1L149)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PCGF4/BMI1 Antibody (1L149) is a Rabbit antibody targeting PCGF4/BMI1. Anti-PCGF4/BMI1 Antibody (1L149) can be used in WB.
Ig Type
IgG
Clone
1L149
Reactivity
Human (predicted:Rat)
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with PCGF4/BMI1 monoclonal antibody, unconjugated (TMAB-10066) at 1: 2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Antigen Details
Immunogen
A synthesized peptide: human BMI1
Antigen Species
Human
Gene Name
BMI1
Gene ID
Protein Name
Polycomb complex protein BMI-1
Uniprot ID
Function
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Chemical Properties
Molecular WeightTheoretical: 37 kDa. Actual: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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