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Anti-IRF4 Antibody (5U89)

😃Good
Catalog No. TMAB-07802

Anti-IRF4 Antibody (5U89) is a Rabbit antibody targeting IRF4. Anti-IRF4 Antibody (5U89) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.

Anti-IRF4 Antibody (5U89)

Anti-IRF4 Antibody (5U89)

😃Good
Catalog No. TMAB-07802
Anti-IRF4 Antibody (5U89) is a Rabbit antibody targeting IRF4. Anti-IRF4 Antibody (5U89) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IRF4 Antibody (5U89) is a Rabbit antibody targeting IRF4. Anti-IRF4 Antibody (5U89) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP,FCM.
Ig Type
IgG
Clone
5U89
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; IP: 1:20-50; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
Tissue SpecificityLymphoid cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundTranscriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells.
Antigen Details
Immunogen
A synthesized peptide: human IRF4
Antigen Species
Human
Gene Name
IRF4
Gene ID
Protein Name
Interferon regulatory factor 4
Uniprot ID
Function
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
Chemical Properties
Molecular WeightTheoretical: 52 kDa. Actual: 52 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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