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Anti-HSD17B10 Antibody (8X842)

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Catalog No. TMAB-07317

Anti-HSD17B10 Antibody (8X842) is a Rabbit antibody targeting HSD17B10. Anti-HSD17B10 Antibody (8X842) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.

Anti-HSD17B10 Antibody (8X842)

Anti-HSD17B10 Antibody (8X842)

😃Good
Catalog No. TMAB-07317
Anti-HSD17B10 Antibody (8X842) is a Rabbit antibody targeting HSD17B10. Anti-HSD17B10 Antibody (8X842) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HSD17B10 Antibody (8X842) is a Rabbit antibody targeting HSD17B10. Anti-HSD17B10 Antibody (8X842) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Ig Type
IgG
Clone
8X842
Reactivity
Human,Mouse,Rat
Application
WB
IHC-P
IHC-Fr
ICC/IF
IF
FCM
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMitochondrion
Tissue SpecificityExpressed in normal tissues but is overexpressed in neurons affected in AD.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMitochondrial dehydrogenase involved in pathways of fatty acid, branched-chain amino acid and steroid metabolism.Acts as (S)-3-hydroxyacyl-CoA dehydrogenase in mitochondrial fatty acid beta-oxidation, a major degradation pathway of fatty acids. Catalyzes the third step in the beta-oxidation cycle, namely the reversible conversion of (S)-3-hydroxyacyl-CoA to 3-ketoacyl-CoA. Preferentially accepts straight medium- and short-chain acyl-CoA substrates with highest efficiency for (3S)-hydroxybutanoyl-CoA.
Antigen Details
Immunogen
A synthesized peptide: human HSD17B10
Antigen Species
Human
Gene Name
HSD17B10
Gene ID
3028
Protein Name
3-hydroxyacyl-CoA dehydrogenase type-2
Uniprot ID
Q99714
Function
Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Chemical Properties
Molecular WeightTheoretical: 27 kDa. Actual: 27 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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