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Anti-Klotho Antibody (8C828) (Synonyms: Klotho, Kl)

Catalog No. TMAC-02333 Copy Product Info
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Anti-Klotho Antibody (8C828) is a Rabbit antibody targeting Klotho. Anti-Klotho Antibody (8C828) can be used in IHC,WB.

Anti-Klotho Antibody (8C828)

Copy Product Info
🥰Excellent
Catalog No. TMAC-02333
Synonyms Klotho, Kl

Anti-Klotho Antibody (8C828) is a Rabbit antibody targeting Klotho. Anti-Klotho Antibody (8C828) can be used in IHC,WB.

Anti-Klotho Antibody
(8C828)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Klotho Antibody (8C828) is a Rabbit antibody targeting Klotho. Anti-Klotho Antibody (8C828) can be used in IHC,WB.
SynonymsKlotho, Kl
Ig Type
IgG
Clone
8C828
Reactivity
Human,Mouse
Verified Activity
1. Western blot analysis of Klotho on human serum lysate using anti-Klotho antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Klotho antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Klotho antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMay have weak glycosidase activity towards glucuronylated steroids. However, it lacks essential active site Glu residues at positions 239 and 872, suggesting it may be inactive as a glycosidase in vivo. May be involved in the regulation of calcium and phosphorus homeostasis by inhibiting the synthesis of active vitamin D. Essential factor for the specific interaction between FGF23 and FGFR1. The Klotho peptide generated by cleavage of the membrane-bound isoform may be an aging circulating hormone which would extend life span by inhibiting insulin/IGF1 signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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