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Anti-UCHL3 Antibody (2M552)

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Catalog No. TMAB-13968 Copy Product Info
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Anti-UCHL3 Antibody (2M552) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (2M552) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Anti-UCHL3 Antibody
(2M552)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-UCHL3 Antibody (2M552) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (2M552) can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
2M552
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
FCM=1:50-100; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityHighly expressed in heart, skeletal muscle, and testis.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundDeubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins.
Antigen Details
Immunogen
A synthesized peptide: human UCHL3
Antigen Species
Human
Gene Name
UCHL3
Gene ID
Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L3
Uniprot ID
Function
Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3". Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory.
Chemical Properties
Molecular WeightTheoretical: 26 kDa. Actual: 26 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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