CD16a Protein, Human, Recombinant (F176V, His) V2

Catalog No. TMPY-01964U

CD16a Protein, Human, Recombinant (F176V, His) V2 is expressed in HEK293 Cells. The accession number is AAH17865.

CD16a Protein, Human, Recombinant (F176V, His) V2

Catalog No. TMPY-01964U

CD16a Protein, Human, Recombinant (F176V, His) V2 is expressed in HEK293 Cells. The accession number is AAH17865.

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Product Information

Biological Activity	Immobilized Human Fc gamma RIIIA (V176), His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-Fc gamma RIIIA Antibody, hFc Tag with the EC50 of 8.8 ng/ml determined by ELISA. (QC Test) Loaded Human Fc gamma RIIIA (V176) , His Tag on Anti-His-Biosensor can bind Trastuzumab, hFc Tag with an affinity constant of 96.30 nM as determined in BLI assay (Gator® Prime).
Description	CD16a Protein, Human, Recombinant (F176V, His) V2 is expressed in HEK293 Cells. The accession number is AAH17865.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	AAH17865
Synonyms	IMD20,IGFR3,FCRIIIA,FCRIII,FCR-10,FCGRIII,FCGR3,FCG3,Fc γ RIIIa,Fc gamma RIIIa,Fc fragment of IgG, low affinity IIIa, receptor (CD16a),CD16A,CD16
Construction	Gly17-Gln208 (V176)
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Molecular Weight	23.4 kDa (Predicted); 45-60 kDa (Due to glycosylation)
Endotoxin	< 0.1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.