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Synonyms: SGBS1SDYS, SGBS-1, SGBS1, SGBS 1, SGBS, SGB, SDYS, OCI-5, OCI5, OCI 5, MXR-7, MXR7, MXR 7, Intestinal protein OCI-5, GTR2-2, GPC-3, GPC3, GPC 3, Glypican-3, Glypican 3, DGSX


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $74 | 7-10 days | 7-10 days | |
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Immobilized Human GPC3, hFc Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Anti-GPC3 Antibody, hFc Tag with the EC50 of 11.0 ng/ml determined by ELISA (QC Test). |
| Description | Glypican 3/GPC3 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P51654-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | P51654-1 |
| Construction | Gln25-His559 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 85% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Synonyms | SGBS1SDYS, SGBS-1, SGBS1, SGBS 1, SGBS, SGB, SDYS, OCI-5, OCI5, OCI 5, MXR-7, MXR7, MXR 7, Intestinal protein OCI-5, GTR2-2, GPC-3, GPC3, GPC 3, Glypican-3, Glypican 3, DGSX |
| Research Background | Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size of ~40 kDa and the C-terminal subunit is ~30 kDa.Glypican 3 is a potential therapeutic target for treating liver cancer and other cancers. Several therapeutic anti-GPC3 antibodies have been developed. |
| Molecular Weight | 86.72 kDa (Predicted); 40-45 kDa, 55-60 kDa and 90-120 kDa (Reducing condition, due to the furin-like convertase cleavage site) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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