Activity has not been tested. It is theoretically active, but we cannot guarantee it.

CDC2L1 Protein, Human, Recombinant (GST) is expressed in Baculovirus-Insect Cells. The accession number is P21127.

Human

Baculovirus-Insect Cells

PITSLREA,Cyclin-dependent kinase 11B,CLK-1,CDK11B,CDK11,CDC2L1

Recombinant full length human CDK11B (CDC2L1) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

>70% as determined by SDS-PAGE.

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Cyclin-dependent kinases (CDKs) are serine/threonine kinases whose activity requires binding of specific cyclin subunits to play critical roles in the control of the cell cycle or transcription. CDKs generally contain a catalytic serine/threonine kinase subunit and a regulatory cyclin subunit, and their activity is dependent on their association with cyclins and endogenous inhibitors (Ink4, Cip/Kip inhibitors), as well as by positive and negative phosphorylation events. Cyclins are periodically synthesized and destroyed during the cell cycle, thereby regulating CDK activity in a timely manner. In mammals, a total of 11 classical CDKs (CDK1-11) and 2 newly proposed family members (CDK12 and CDK13), as well as other proteins with structure or function similar to that of CDKs have been identified to date.