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Anti-HIP1 Antibody (5F230)

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Catalog No. TMAB-07042

Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP.

Anti-HIP1 Antibody (5F230)

Anti-HIP1 Antibody (5F230)

😃Good
Catalog No. TMAB-07042
Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4707-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP.
Ig Type
IgG
Clone
5F230
Reactivity
Human,Mouse,Rat
Application
WB
ICC/IF
IP
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Shuttles between cytoplasm and nucleus. Nuclear translocation can be induced by AR.
Tissue SpecificityUbiquitously expressed with the highest level in brain. Expression is up-regulated in prostate and colon cancer.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPlays a role in clathrin-mediated endocytosis and trafficking .Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner.Regulates presynaptic nerve terminal activity.
Antigen Details
Immunogen
A synthesized peptide: human HIP 1
Antigen Species
Human
Gene Name
HIP1
Gene ID
3092
Protein Name
Huntingtin-interacting protein 1
Uniprot ID
O00291
Function
Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Chemical Properties
Molecular WeightTheoretical: 116 kDa. Actual: 116 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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