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Anti-HIP1 Antibody (5F230)
Catalog No. TMAB-07042 Copy Product Info
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Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP.
Anti-HIP1 Antibody (5F230)
Copy Product Info🥰Excellent
Catalog No. TMAB-07042
Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP.
Anti-HIP1 Antibody
(5F230)
(5F230)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μL | $151 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-HIP1 Antibody (5F230) is a Rabbit antibody targeting HIP1. Anti-HIP1 Antibody (5F230) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Clone | 5F230 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with HIP1 monoclonal antibody, unconjugated (TMAB-07042) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Endomembrane system. Cytoplasmic vesicle > clathrin-coated vesicle membrane. Shuttles between cytoplasm and nucleus. Nuclear translocation can be induced by AR. |
| Tissue Specificity | Ubiquitously expressed with the highest level in brain. Expression is up-regulated in prostate and colon cancer. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Plays a role in clathrin-mediated endocytosis and trafficking .Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner.Regulates presynaptic nerve terminal activity. |
| Immunogen | A synthesized peptide: human HIP 1 |
| Antigen Species | Human |
| Gene Name | HIP1 |
| Gene ID | |
| Protein Name | Huntingtin-interacting protein 1 |
| Uniprot ID | |
| Function | Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors. |
| Molecular Weight | Theoretical: 116 kDa. Actual: 116 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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