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Anti-Tyrosinase Antibody (1S147)

Catalog No. TMAB-13912 Copy Product Info
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Anti-Tyrosinase Antibody (1S147) is a Rabbit antibody targeting Tyrosinase. Anti-Tyrosinase Antibody (1S147) can be used in WB.

Anti-Tyrosinase Antibody (1S147)

Copy Product Info
🥰Excellent
Catalog No. TMAB-13912

Anti-Tyrosinase Antibody (1S147) is a Rabbit antibody targeting Tyrosinase. Anti-Tyrosinase Antibody (1S147) can be used in WB.

Anti-Tyrosinase Antibody
(1S147)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Tyrosinase Antibody (1S147) is a Rabbit antibody targeting Tyrosinase. Anti-Tyrosinase Antibody (1S147) can be used in WB.
Ig Type
IgG
Clone
1S147
Reactivity
Human
Verified Activity
25 μg total protein per lane of various lysates (see on figure) probed with Tyrosinase monoclonal antibody, unconjugated (TMAB-13912) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMelanosome membrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundThis is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone.
Antigen Details
Immunogen
A synthesized peptide: human Tyrosinase
Antigen Species
Human
Gene Name
TYR
Gene ID
Protein Name
Tyrosinase
Uniprot ID
Function
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Chemical Properties
Molecular WeightTheoretical: 60 kDa. Actual: 70-80 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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