IL-31 Protein, Canine, Recombinant (His)

Name: IL-31 Protein, Canine, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01733
Rating: 4.5 (1 reviews)

(Synonyms: Interleukin-31, IL-31, IL31) Copy Product Info

Synonyms: Interleukin-31, IL-31, IL31

Catalog No. TMPK-01733 Copy Product Info

IL-31 Protein, Canine, Recombinant (His) is expressed in HEK293 Cells. The accession number is BAH97742.1.

Customer service consultation

Pack Size	Price	USA Stock	Global Stock
5 µg	$74	7-10 days	7-10 days
10 µg	$113	7-10 days	7-10 days
20 µg	$175	7-10 days	7-10 days
50 µg	$316	7-10 days	7-10 days
100 µg	$490	7-10 days	7-10 days
200 µg	$793	7-10 days	7-10 days
500 µg	$1,470	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Bioactivity

Bioactivity	Measured by a reporter gene assay. The ED50 for this effect is <10 ng/ml.
Description	IL-31 Protein, Canine, Recombinant (His) is expressed in HEK293 Cells. The accession number is BAH97742.1.
Species	Canine
Expression System	HEK293 Cells
Tag	N-His
Accession Number	BAH97742.1
Construction	Ala27-Gln159
Protein Purity	> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Endotoxin	< 1 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Interleukin-31, IL-31, IL31
Research Background	Many autoimmune skin diseases, such as bullous pemphigoid (BP), psoriasis and certain types of chronic urticaria, are associated with intensive pruritus. While histamine and neuropeptides have previously been ascribed to play a role in itch that accompanies these diseases, recent evidence suggests that the pruritogenic cytokine interleukin (IL)-31 is a major driver of pruritic responses. IL-31 was originally shown to be produced by activated helper T cells, particularly Th2 cells, mast cells, macrophages and dendritic cells.

Chemical Properties

Molecular Weight

16.63 kDa (Predicted); 26-36 kDa (Reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.