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Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
| Description | Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP. |
| Ig Type | IgG |
| Clone | 7D535 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Tissue Specificity | Expressed predominantly in peripheral blood lymphocytes. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells. |
| Immunogen | A synthesized peptide: human IRAK3 |
| Antigen Species | Human |
| Gene Name | IRAK3 |
| Gene ID | |
| Protein Name | Interleukin-1 receptor-associated kinase 3 |
| Uniprot ID | |
| Function | Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex. |
| Molecular Weight | Theoretical: 68 kDa. Actual: 68 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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