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Anti-IRAKM Antibody (7D535)

😃Good
Catalog No. TMAB-07793

Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.

Anti-IRAKM Antibody (7D535)

Anti-IRAKM Antibody (7D535)

😃Good
Catalog No. TMAB-07793
Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.
Ig Type
IgG
Clone
7D535
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-2000; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityExpressed predominantly in peripheral blood lymphocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPutative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.
Antigen Details
Immunogen
A synthesized peptide: human IRAK3
Antigen Species
Human
Gene Name
IRAK3
Gene ID
Protein Name
Interleukin-1 receptor-associated kinase 3
Uniprot ID
Function
Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Chemical Properties
Molecular WeightTheoretical: 68 kDa. Actual: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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