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Anti-IRAKM Antibody (7D535)

Catalog No. TMAB-07793 Copy Product Info
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Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.

Anti-IRAKM Antibody (7D535)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07793

Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.

Anti-IRAKM Antibody
(7D535)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IRAKM Antibody (7D535) is a Rabbit antibody targeting IRAKM. Anti-IRAKM Antibody (7D535) can be used in WB,IP.
Ig Type
IgG
Clone
7D535
Reactivity
Human
Verified Activity
Western blot analysis of A431 cell lysate. Using IRAKM (TMAB-07793) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
Application
Recommended Dose
WB: 1:1000-2000; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Tissue SpecificityExpressed predominantly in peripheral blood lymphocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundPutative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.
Antigen Details
Immunogen
A synthesized peptide: human IRAK3
Antigen Species
Human
Gene Name
IRAK3
Gene ID
Protein Name
Interleukin-1 receptor-associated kinase 3
Uniprot ID
Function
Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Chemical Properties
Molecular WeightTheoretical: 68 kDa. Actual: 68 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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