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Anti-CYFIP1 Antibody (1Z411)

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Catalog No. TMAB-04859

Anti-CYFIP1 Antibody (1Z411) is a Rabbit antibody targeting CYFIP1. Anti-CYFIP1 Antibody (1Z411) can be used in FCM, ICC/IF, WB.

Anti-CYFIP1 Antibody (1Z411)

Anti-CYFIP1 Antibody (1Z411)

😃Good
Catalog No. TMAB-04859
Anti-CYFIP1 Antibody (1Z411) is a Rabbit antibody targeting CYFIP1. Anti-CYFIP1 Antibody (1Z411) can be used in FCM, ICC/IF, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CYFIP1 Antibody (1Z411) is a Rabbit antibody targeting CYFIP1. Anti-CYFIP1 Antibody (1Z411) can be used in FCM, ICC/IF, WB.
Ig Type
IgG
Clone
1Z411
Reactivity
Human,Mouse,Rat
Application
FCM
ICC/IF
WB
Recommended Dose
FCM=1:50-100; ICC/IF=1:50-200; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm > perinuclear region. Cell projection > lamellipodium. Cell projection > ruffle. Cell junction > synapse > synaptosome. Highly expressed in the perinuclear region. Enriched in synaptosomes, membrane ruffles and at the tips of lamellipodia.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundComponent of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity).
Antigen Details
Immunogen
A synthesized peptide: human CYFIP1
Antigen Species
Human
Gene Name
CYFIP1
Gene ID
23191
Protein Name
Cytoplasmic FMR1-interacting protein 1
Uniprot ID
Q7L576
Function
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Involved in formation of membrane ruffles and lamellipodia protrusions and in axon outgrowth. Binds to F-actin but not to RNA. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers.
Chemical Properties
Molecular WeightTheoretical: 145 kDa. Actual: 130 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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