Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Eleutherin

Name: Eleutherin
Brand: TargetMol
SKU: TN2464
Rating: 4.5 (1 reviews)

😃Good

Catalog No. TN2464Cas No. 478-36-4

Alias Anti-Human IL17A/IL-17F Recombinant Antibody

Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.

Eleutherin

😃Good

Purity: 99.57%

Catalog No. TN2464Alias Anti-Human IL17A/IL-17F Recombinant AntibodyCas No. 478-36-4

Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
200 mg	$445	Inquiry	Inquiry

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.57%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.
Targets&IC50	C6 cells:4.98 μM
In vitro	Methods: The MTT assay was used to investigate the effects of eleutherine (0.025-50μM) on C6 cell viability. Results: Eleutherine showed dose- and time-dependent cytotoxicity toward C6 cells, with IC50 values decreasing as treatment duration increased.[1]
Synonyms	Anti-Human IL17A/IL-17F Recombinant Antibody

Chemical Properties

Molecular Weight	272.3
Formula	C₁₆H₁₆O₄
Cas No.	478-36-4
Smiles	O=C1C=2C(C(=O)C3=C1[C@@H](C)O[C@@H](C)C3)=CC=CC2OC
Relative Density.	1.25 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 12 mg/mL (44.07 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 1 mg/mL (3.67 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6724 mL	18.3621 mL	36.7242 mL	183.6210 mL
5 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
10 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
20 mM	0.1836 mL	0.9181 mL	1.8362 mL	9.1811 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc