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Eleutherin

Name: Eleutherin
Brand: TargetMol
SKU: TN2464
Rating: 4.5 (1 reviews)

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Catalog No. TN2464Cas No. 478-36-4

Alias Anti-Human IL17A/IL-17F Recombinant Antibody

Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.

Eleutherin

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Purity: 99.571%

Catalog No. TN2464Alias Anti-Human IL17A/IL-17F Recombinant AntibodyCas No. 478-36-4

Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.

Pack Size	Price	Availability	Quantity
200 mg	$445	Backorder

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Purity:99.571%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Eleutherin, a natural naphthoquinone derivative, exerts protective effects on human umbilical vein endothelial cells (HUVECs) and inhibits carrageenan-induced hyperalgesia in mice.
Targets&IC50	C6 cells:4.98 μM
In vitro	Methods: The MTT assay was used to investigate the effects of eleutherine (0.025-50μM) on C6 cell viability. Results: Eleutherine showed dose- and time-dependent cytotoxicity toward C6 cells, with IC50 values decreasing as treatment duration increased.[1]
Synonyms	Anti-Human IL17A/IL-17F Recombinant Antibody

Chemical Properties

Molecular Weight	272.3
Formula	C₁₆H₁₆O₄
Cas No.	478-36-4
Smiles	O=C1C=2C(C(=O)C3=C1[C@@H](C)O[C@@H](C)C3)=CC=CC2OC
Relative Density.	1.25 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 12 mg/mL (44.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6724 mL	18.3621 mL	36.7242 mL	183.6210 mL
5 mM	0.7345 mL	3.6724 mL	7.3448 mL	36.7242 mL
10 mM	0.3672 mL	1.8362 mL	3.6724 mL	18.3621 mL
20 mM	0.1836 mL	0.9181 mL	1.8362 mL	9.1811 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc