Immobilized Human Her3, His Tag at 2 μg/ml (100 μl/well) on the plate. Dose response curve for Human NRG1 Beta 1, hFc Tag with the EC50 of 26.9 ng/ml determined by ELISA.
Immobilized Human Her3, His Tag at 0.5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-HER3 Antibody, hFc Tag with the EC50 of 3.2 ng/ml determined by ELISA.

HER3/ERBB3 Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P21860-1.

Human

HEK293 Cells

p85-sErbB3,p45-sErbB3,p180-ErbB3,MDA-BF-1,LCCS2,HER3,erbB3-S,ErbB-3,erb-b2 receptor tyrosine kinase 3,EEBB3,c-erbB-3,c-erbB3

Ser20-Thr643

> 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Her3, also called ErbB3, is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. Her3 is expressed in keratinocytes, melanocytes, skeletal muscle cells, embryonic myoblasts and Schwann cells. Monomeric Her3 serves as a low affinity receptor for the heregulins (HRG).