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Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P04202.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 μg | $54 | 7-10 days | 7-10 days | |
| 10 μg | $85 | 7-10 days | 7-10 days | |
| 20 μg | $137 | 7-10 days | 7-10 days | |
| 50 μg | $267 | 7-10 days | 7-10 days | |
| 100 μg | $447 | 7-10 days | 7-10 days | |
| 200 μg | $763 | 7-10 days | 7-10 days | |
| 500 μg | $1,530 | 7-10 days | 7-10 days |
| Biological Activity | Immobilized Mouse Latent TGF beta 1, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Biotinylated Human ITGAV&ITGB6, hFc Tag with the EC50 of 0.59 μg/ml determined by ELISA. |
| Description | Latent TGF beta 1 Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P04202. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Accession Number | P04202 |
| Synonyms | transforming growth factor, β1,transforming growth factor, beta 1,TGF-β1,TGFβ1,TGF-beta1,TGFbeta1,Tgfb-1,Tgfb,TGF β1 |
| Construction | Leu30-Ser390 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE |
| Molecular Weight | 29.5/12.9 kDa (Predicted); 40-50/14-15 kDa (Due to glycosylation) |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Latent TGF beta 1 cDNA encodes a 390 amino acid precursor that contains a 29 aa signal peptide and a 361 aa proprotein. A furin‑like convertase processes the proprotein to generate an N‑terminal 249 aa latency‑associated peptide (LAP) and a C‑terminal 112 aa mature TGF‑ beta 1. Disulfide‑linked homodimers of LAP and TGF‑ beta 1 remain non‑covalently associated after secretion, forming the small latent TGF‑ beta 1 complex. |
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