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Anti-CYCS Antibody (7T202) (Synonyms: Cytochrome C, CYCS, CYC)

Catalog No. TMAC-01068 Copy Product Info
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Anti-CYCS Antibody (7T202) is a Rabbit antibody targeting CYCS. Anti-CYCS Antibody (7T202) can be used in ICC/IF,IHC,IP,WB.

Anti-CYCS Antibody (7T202)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01068
Synonyms Cytochrome C, CYCS, CYC

Anti-CYCS Antibody (7T202) is a Rabbit antibody targeting CYCS. Anti-CYCS Antibody (7T202) can be used in ICC/IF,IHC,IP,WB.

Anti-CYCS Antibody
(7T202)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CYCS Antibody (7T202) is a Rabbit antibody targeting CYCS. Anti-CYCS Antibody (7T202) can be used in ICC/IF,IHC,IP,WB.
SynonymsCytochrome C, CYCS, CYC
Ig Type
IgG
Clone
7T202
Reactivity
Human,Mouse,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded mouse liver tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Cytochrome C antibody. Counter stained with hematoxylin.
5. ICC staining Cytochrome C in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCytochrome c is a well characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial intermembrane space. More recent studies have identifed cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is translocated from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 14 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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