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Anti-PAF1 Antibody (8R789)
😃Good
Catalog No. TMAB-09922
Anti-PAF1 Antibody (8R789) is a Rabbit antibody targeting PAF1. Anti-PAF1 Antibody (8R789) can be used in WB.
Anti-PAF1 Antibody (8R789)
Anti-PAF1 Antibody (8R789)
😃Good
Catalog No. TMAB-09922
Anti-PAF1 Antibody (8R789) is a Rabbit antibody targeting PAF1. Anti-PAF1 Antibody (8R789) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $473 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PAF1 Antibody (8R789) is a Rabbit antibody targeting PAF1. Anti-PAF1 Antibody (8R789) can be used in WB. |
| Ig Type | IgG |
| Clone | 8R789 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. |
| Immunogen | A synthesized peptide: human PAF1 |
| Antigen Species | Human |
| Gene Name | PAF1 |
| Gene ID | |
| Protein Name | RNA polymerase II-associated factor 1 homolog |
| Uniprot ID | |
| Function | The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo and in vitro. |
| Molecular Weight | Theoretical: 60 kDa. Actual: 80 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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