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Anti-API2/BIRC3 Antibody (3Y355)

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Catalog No. TMAB-02746

Anti-API2/BIRC3 Antibody (3Y355) is a Rabbit antibody targeting API2/BIRC3. Anti-API2/BIRC3 Antibody (3Y355) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.

Anti-API2/BIRC3 Antibody (3Y355)

Anti-API2/BIRC3 Antibody (3Y355)

😃Good
Catalog No. TMAB-02746
Anti-API2/BIRC3 Antibody (3Y355) is a Rabbit antibody targeting API2/BIRC3. Anti-API2/BIRC3 Antibody (3Y355) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1507-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4737-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-API2/BIRC3 Antibody (3Y355) is a Rabbit antibody targeting API2/BIRC3. Anti-API2/BIRC3 Antibody (3Y355) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,IP.
Ig Type
IgG
Clone
3Y355
Reactivity
Human
Application
WB
IHC-P
IHC-Fr
ICC/IF
IF
IP
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-100; IF: 1:50-200; IP: 1:20-50
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus.
Tissue SpecificityHighly expressed in fetal lung, and kidney. In the adult, expression is mainly seen in lymphoid tissues, including spleen, thymus and peripheral blood lymphocytes.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMulti-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, mitogenic kinase signaling and cell proliferation, as well as cell invasion and metastasis. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and regulates both canonical and non-canonical NF-kappa-B signaling by acting in opposite directions: acts as a positive regulator of the canonical pathway and suppresses constitutive activation of non-canonical NF-kappa-B signaling.
Antigen Details
Immunogen
A synthesized peptide: human BIRC3
Antigen Species
Human
Gene Name
BIRC3
Gene ID
330
Protein Name
Baculoviral IAP repeat-containing protein 3
Uniprot ID
Q13489
Function
Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Chemical Properties
Molecular WeightTheoretical: 68 kDa. Actual: 72 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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