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Anti-GNB3 Antibody (4P59)

Catalog No. TMAB-06611 Copy Product Info
🥰Excellent
Anti-GNB3 Antibody (4P59) is a Mouse antibody targeting GNB3. Anti-GNB3 Antibody (4P59) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.

Anti-GNB3 Antibody (4P59)

Copy Product Info
🥰Excellent
Catalog No. TMAB-06611

Anti-GNB3 Antibody (4P59) is a Mouse antibody targeting GNB3. Anti-GNB3 Antibody (4P59) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.

Anti-GNB3 Antibody
(4P59)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GNB3 Antibody (4P59) is a Mouse antibody targeting GNB3. Anti-GNB3 Antibody (4P59) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG1, Kappa
Clone
4P59
Reactivity
Human (predicted:Mouse,Rat)
Verified Activity
1. Tissue: Human liver cancer
Section type: Formalin fixed & Paraffin-embedded section
Retrieval method: High temperature and high pressure
Retrieval buffer: Tris/EDTA buffer, pH 9.0 Primary ab dilution: 1:100
Primary ab incubation condition: 1 hour at room temperature
Secondary ab: SP Kit (Mouse)
Counter stain: Hematoxylin (Blue)
Comment: Color brown is the positive signal for TMAB-06611
2. Cell line: HepG2
Fixative: 4% Paraformaldehyde
Permeabilization: 0.1% TritonX-100
Primary ab dilution: 1:50
Primary incubation condition: 4°C overnight
Secondary ab: Goat Anti-Rabbit IgG
Nuclear counter stain: DAPI (Blue)
Comment: Color green is the positive signal for TMAB-06611
Application
Recommended Dose
WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundG proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
Antigen Details
Gene Name
GNB3
Gene ID
Protein Name
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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