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Anti-KRT17 Antibody (9X387)
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Catalog No. TMAC-01079
Alias type I cytoskeletal 17, PCHC1, PC2, PC, KRT 17, Keratin-17, keratin, type i cytoskeletal 17 [version 1], Keratin type I cytoskeletal 17, Keratin 17, type I, keratin 17 epitope S4, keratin 17 epitope S2, keratin 17 epitope S1, Keratin 17, Keratin, K1C17_HUMAN, K17, Cytokeratin-17, CK-17, CK 17, 39.1
Anti-KRT17 Antibody (9X387) is a Rabbit antibody targeting KRT17. Anti-KRT17 Antibody (9X387) can be used in WB,ICC/IF,IHC,FCM.
Anti-KRT17 Antibody (9X387)
Anti-KRT17 Antibody (9X387)
😃Good
Catalog No. TMAC-01079Alias type I cytoskeletal 17, PCHC1, PC2, PC, KRT 17, Keratin-17, keratin, type i cytoskeletal 17 [version 1], Keratin type I cytoskeletal 17, Keratin 17, type I, keratin 17 epitope S4, keratin 17 epitope S2, keratin 17 epitope S1, Keratin 17, Keratin, K1C17_HUMAN, K17, Cytokeratin-17, CK-17, CK 17, 39.1
Anti-KRT17 Antibody (9X387) is a Rabbit antibody targeting KRT17. Anti-KRT17 Antibody (9X387) can be used in WB,ICC/IF,IHC,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-KRT17 Antibody (9X387) is a Rabbit antibody targeting KRT17. Anti-KRT17 Antibody (9X387) can be used in WB,ICC/IF,IHC,FCM. |
| Synonyms | type I cytoskeletal 17, PCHC1, PC2, PC, KRT 17, Keratin-17, keratin, type i cytoskeletal 17 [version 1], Keratin type I cytoskeletal 17, Keratin 17, type I, keratin 17 epitope S4, keratin 17 epitope S2, keratin 17 epitope S1, Keratin 17, Keratin, K1C17_HUMAN, K17, Cytokeratin-17, CK-17, CK 17, 39.1 |
| Ig Type | IgG |
| Clone | 9X387 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Cytokeratin 17 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Cytokeratin 17 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-Cytokeratin 17 antibody. Counter stained with hematoxylin. 4. ICC staining Cytokeratin 17 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. ICC staining Cytokeratin 17 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 6. Flow cytometric analysis of Hela cells with Cytokeratin 17 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 48 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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