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Synonyms: type I cytoskeletal 17, PCHC1, PC2, PC, KRT 17, Keratin-17, keratin, type i cytoskeletal 17 [version 1], Keratin type I cytoskeletal 17, Keratin 17, type I, keratin 17 epitope S4, keratin 17 epitope S2, keratin 17 epitope S1, Keratin 17, Keratin, K1C17_HUMAN, K17, Cytokeratin-17, CK-17, CK 17, 39.1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
| Description | Anti-KRT17 Antibody (9X387) is a Rabbit antibody targeting KRT17. Anti-KRT17 Antibody (9X387) can be used in FCM,ICC/IF,IHC,WB. |
| Synonyms | type I cytoskeletal 17, PCHC1, PC2, PC, KRT 17, Keratin-17, keratin, type i cytoskeletal 17 [version 1], Keratin type I cytoskeletal 17, Keratin 17, type I, keratin 17 epitope S4, keratin 17 epitope S2, keratin 17 epitope S1, Keratin 17, Keratin, K1C17_HUMAN, K17, Cytokeratin-17, CK-17, CK 17, 39.1 |
| Ig Type | IgG |
| Clone | 9X387 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Cytokeratin 17 is a member of the Cytokeratin subfamily of intermediate filament proteins (IFPs). It is unique in that it is normally expressed in the basal cells of complex epithelia but not in stratified or simple epithelia. Cytokeratin 17 contains 432 amino acids and is expressed in the nail bed, hair follicle, sebaceous glands and other epidermal appendages. Cytokeratin 17 functions to regulate cell growth and size through its interactions with the adaptor protein 14-3-3-sigma to mediate protein synthesis. Mutations in the gene encoding for Cytokeratin 17 lead to depressed protein translation and smaller sized skin keratinocytes, corresponding to decreased Akt/mTOR signaling activity. Cytokeratin 17 may be a useful marker for cervical stem cell identification, squamous cell carcinoma of the larynx, respiratory syncytial virus and transitional cell carcinomas of the human urinary tract. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 48 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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