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ADC Naked Antibody

ADC Antibodies are highly specific antibodies designed for antibody-drug conjugate development, offering optimal target binding, stability, and conjugation compatibility. ADC Antibodies serve as the essential targeting component of ADCs.

Trastuzumab
T9912180288-69-1
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.
  • $157
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Cetuximab
Cetuximab (anti-EGFR), C225
T9905205923-56-4
Cetuximab (C225) is a monoclonal antibody that is an inhibitor of human epidermal growth factor receptor (EGFR) (Kd=0.201 nM). Cetuximab has antitumor activity, inhibiting tumor cell proliferation and inducing apoptosis.
  • $197
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Atezolizumab
T99021380723-44-3
Atezolizumab is an antibody inhibitor, a humanized monoclonal antibody, IgG1, which targets PD-L1 and blocks the interaction of PD-L1 with PD-1. Atezolizumab has antitumor activity and promotes T-cells to attack tumor cells.
  • $228
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Brentuximab
T767182088770-90-3
Brentuximab, a chimeric antibody targeting CD30, is a naked antibody to Brentuximab vedotin. It possesses antitumor activity and may be used to study relapsed or refractory Hodgkin's lymphoma.
  • $297
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TargetMol | Inhibitor Hot
Telisotuzumab
Mab-224G11, ABT-700
T774371781223-80-0
Telisotuzumab(ABT-700) is a humanized recombinant antibody targeting the therapeutic hepatocyte growth factor receptor (MET) with high affinity for c-Met.Telisotuzumab has inhibitory effects on c-Met signaling and antitumor activity.
  • $372
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Sacituzumab
Sacituzumab (anti-Trop-2), Sacituzumab
T353971796566-95-4
Sacituzumab (hRS7) is an antibody inhibitor and a humanized monoclonal antibody targeting trophoblast cell surface antigen 2 (TROP2), serving as a component of the antibody-drug conjugate sacituzumab govitecan, used for research and treatment of TROP2-high-expressing tumors such as triple-negative breast cancer.
  • $163
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TargetMol | Inhibitor Hot
Rituximab
T9910174722-31-7
Rituximab is an anti-CD20 chimeric monoclonal antibody used to study certain autoimmune diseases and cancers.
  • $229
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TargetMol | Inhibitor Hot
TargetMol | Citations Cited
Milatuzumab
MEDI-115, hLL1
T77478899796-83-9
Milatuzumab (MEDI-115) is a humanized monoclonal antibody against CD74. Milatuzumab promotes the production of free radical oxygen and the loss of mitochondrial membrane potential, reduces CD20/CD74 aggregates and cell adhesion, and induces cell death.
  • $228
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Datopotamab
T9901A-0072267989-53-5
Datopotamab (CDP7657) is a TROP2-targeting antibody that is a naked antibody to Datopotamab deruxtecan and can be used to synthesize active antibody conjugators (Datopotamab deruxtecan). Datopotamab is being investigated for use in triple-negative breast cancer and non-small cell lung cancer.
  • $255
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Mirvetuximab
M9346A
T767661453084-36-0
Mirvetuximab (M9346A) is a novel folate receptor α (FRα) monoclonal antibody targeting anti-FOLR1 (folate receptor 1). Mirvetuximab soravtansine is often conjugated with platinum compounds or other compounds to form antibody-drug conjugates for the treatment of ovarian cancer and other FRα-positive cancers.
  • $322
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Tisotumab
T773721418628-81-5
Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody targeting tissue factor (TF), utilized in antibody-conjugating drugs for cancer research.
  • $263
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Anetumab
T768571954758-84-9
Anetumab is a novel fully human anti-mesothelin IgG1 antibody that is a naked antibody to Anetumab ravtansine.Anetumab can be used to synthesize the antibody-activated molecule coupling, Anetumab ravtansine.Anetumab can be used to study the treatment of metastatic pleural mesothelioma.
  • $247
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Gemtuzumab
CMA-676, CDP-771
T9901A-0032924764-21-4
Gemtuzumab(CMA-676) is a monoclonal antibody directed against the CD33 antigen and consists of a recombinant humanized IgG4 antibody.Gemtuzumab can be used to synthesize Gemtuzumab ozogamicin, an antibody coupled compound (ADC) Gemtuzumab is used in the study of acute myeloid leukemia.
  • $282
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Enfortumab
T774051448664-46-7
Enfortumab is a monoclonal antibody against Nectin-4.Enfortumab can be used to synthesize antibody-drug couplings (enfortumab vedotin) and can also be used in conjunction with platinum compounds to study uroepithelial cancers.
  • $228
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TargetMol | Inhibitor Hot
Zilovertamab
UC-961, Cirmtuzumab, 1643432-38-5
T767492485779-13-1
Zilovertamab (UC-961) is a humanized anti-ROR1 monoclonal antibody that cuts off the WNT5A-induced ROR1 signaling pathway and shows anti-proliferative activity in ovarian and endometrial cancer cells. It can be used to study lymphatic cancer.
  • $247
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Samrotamab
PR-1498487, PR1498487
T77414
Samrotamab (PR-1498487) is a humanized anti-LRRC15 antibody that can be used to synthesize the ADC compound (Samrotamab vedotin).
  • $330
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Rovalpituzumab
T766981613313-01-1
Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3) and is utilized to synthesize antibody-active molecule conjugates (ADCs). It exhibits anticancer activity and is used in the treatment of small cell lung cancer (SCLC).
  • $178
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Aprutumab
FGFR-moAb, FGFR2-TTC, BAY 1179470
T766721634620-63-5
Aprutumab (BAY 1179470) is a human FGFR2 monoclonal antibody with affinity to FGFR2 isoforms FGFR2-IIIB and FGFR2-IIIC. Aprutumab is commonly used to synthesize antibody-drug conjugates.
  • $479
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Losatuxizumab
ABT-806, ABT806
T770731801544-27-3
Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody that is a naked antibody to the ADC compound Losatuxizumab vedotin, with potential anti-tumor activity for the study of advanced malignant solid tumors.
  • $197
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Belantamab
GSK2857914
T771292061894-48-0
Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantamab mafodotin).
  • $263
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Vadastuximab
Anti-Human CD33 Recombinant Antibody
T77389
Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody that can be used for the synthesis of the ADC compound Vadastuximab talirine and for the study of acute myeloid leukemia (AML).
  • $328
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Patritumab
U3-1287, AMG-888
T767961262787-83-6
Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-small cell lung cancer.
  • $297
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Naratuximab
Anti-TSPAN26/CD37 Reference Antibody
T817031622327-39-2
Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize the ADC compound Naratuximab emtansine.
  • $189
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Codrituzumab
RO5137382, RG-7686, GC33
T774401365267-33-9
Codrituzumab (GC3) is a humanized antibody against the glypican-3 hepatocellular carcinoma protein that can be used in combination with sorafenib to study incurable advanced hepatocellular carcinoma (HCC).
  • $147
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