IL-17A Protein, Human, Recombinant V2

Name: IL-17A Protein, Human, Recombinant V2
Brand: TargetMol
SKU: TMPY-02886U
Rating: 4.5 (1 reviews)

(Synonyms: interleukin 17A, IL-17A, IL-17, IL17, CTLA-8, CTLA8) Copy Product Info

Synonyms: interleukin 17A, IL-17A, IL-17, IL17, CTLA-8, CTLA8

Catalog No. TMPY-02886U Copy Product Info

IL-17A Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q16552.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$48	7-10 days	7-10 days
10 µg	$80	7-10 days	7-10 days
20 µg	$130	7-10 days	7-10 days
50 µg	$243	7-10 days	7-10 days
100 µg	$396	7-10 days	7-10 days
200 µg	$700	7-10 days	7-10 days
500 µg	$1,480	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:Greater than 95% as determined by reducing SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Human AXL-His at 10μg/ml (100 μl/well) can bind Human GAS6-His.: Biotinylated by NHS-biotin prior to testing The ED50 of Recombinant Human GAS6-His* is 0.04466 ug/ml. (Regularly tested)
Description	IL-17A Protein, Human, Recombinant V2 is expressed in E. coli. The accession number is Q16552.
Species	Human
Expression System	E. coli
Tag	Tag Free
Accession Number	Q16552
Construction	Gly24-Ala155
Protein Purity	> 95% as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	interleukin 17A, IL-17A, IL-17, IL17, CTLA-8, CTLA8
Research Background	Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumatoid arthritis synovium. It increases IL-6 production, induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage. IL-17 is also able to increase bone destruction and reduce its formation. Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.

Chemical Properties

Molecular Weight

15.26 kDa (Predicted); 16 kDa (Reducing conditions)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.