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Anti-DCP1A Antibody (1X787)
😃Good
Catalog No. TMAB-05008
Anti-DCP1A Antibody (1X787) is a Rabbit antibody targeting DCP1A. Anti-DCP1A Antibody (1X787) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
Anti-DCP1A Antibody (1X787)
Anti-DCP1A Antibody (1X787)
😃Good
Catalog No. TMAB-05008
Anti-DCP1A Antibody (1X787) is a Rabbit antibody targeting DCP1A. Anti-DCP1A Antibody (1X787) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-DCP1A Antibody (1X787) is a Rabbit antibody targeting DCP1A. Anti-DCP1A Antibody (1X787) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
| Ig Type | IgG |
| Clone | 1X787 |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, P-body. Nucleus. Co-localizes with NANOS3 in the processing bodies. Predominantly cytoplasmic, in processing bodies (PB). Nuclear, after TGFB1 treatment. Translocation to the nucleus depends on interaction with SMAD4. |
| Tissue Specificity | Detected in heart, brain, placenta, lung, skeletal muscle, liver, kidney and pancreas. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay.Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.Contributes to the transactivation of target genes after stimulation by TGFB1. |
| Immunogen | A synthesized peptide: human DCP1A |
| Antigen Species | Human |
| Gene Name | DCP1A |
| Gene ID | |
| Protein Name | mRNA-decapping enzyme 1A |
| Uniprot ID | |
| Function | Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1. |
| Molecular Weight | Theoretical: 63 kDa. Actual: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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