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Anti-GRK6 Antibody (5G602)
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Catalog No. TMAB-06785
Anti-GRK6 Antibody (5G602) is a Rabbit antibody targeting GRK6. Anti-GRK6 Antibody (5G602) can be used in WB.
Anti-GRK6 Antibody (5G602)
Anti-GRK6 Antibody (5G602)
Copy Product Info😃Good
Catalog No. TMAB-06785
Anti-GRK6 Antibody (5G602) is a Rabbit antibody targeting GRK6. Anti-GRK6 Antibody (5G602) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $264 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GRK6 Antibody (5G602) is a Rabbit antibody targeting GRK6. Anti-GRK6 Antibody (5G602) can be used in WB. |
| Ig Type | IgG |
| Clone | 5G602 |
| Reactivity | Human,Mouse |
| Verified Activity | Western blot analysis of Ramos cell lysate. Using GRK6 (TMAB-06785) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Lipid-anchor. |
| Tissue Specificity | Widely expressed. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis.Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Immunogen | A synthesized peptide: human GRK6 |
| Antigen Species | Human |
| Gene Name | GRK6 |
| Gene ID | |
| Protein Name | G protein-coupled receptor kinase 6 |
| Uniprot ID | |
| Function | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamin receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro). |
| Molecular Weight | Theoretical: 66 kDa. Actual: 66 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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