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Anti-IL-8 Antibody (7N489)

Catalog No. TMAB-07675 Copy Product Info
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Anti-IL-8 Antibody (7N489) is a Rabbit antibody targeting IL-8. Anti-IL-8 Antibody (7N489) can be used in IHC-P.

Anti-IL-8 Antibody (7N489)

Copy Product Info
🥰Excellent
Catalog No. TMAB-07675

Anti-IL-8 Antibody (7N489) is a Rabbit antibody targeting IL-8. Anti-IL-8 Antibody (7N489) can be used in IHC-P.

Anti-IL-8 Antibody
(7N489)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2647-10 days7-10 days
100 μL$4707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-8 Antibody (7N489) is a Rabbit antibody targeting IL-8. Anti-IL-8 Antibody (7N489) can be used in IHC-P.
Ig Type
IgG
Clone
7N489
Reactivity
Human
Verified Activity
Paraformaldehyde-fixed, paraffin embedded Human Chronic tonsillitis; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; The section was incubated with IL-8 Monoclonal Antibody, Unconjugated (TMAB-07675) at 1: 200 overnight at 4°C, followed by conjugation to the Goat Anti-Rabbit IgG H&L Secondary Antibody-HRP and DAB staining.
Application
Recommended Dose
IHC-P: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundChemotactic factor that mediates inflammatory response by attracting neutrophils, basophils, and T-cells to clear pathogens and protect the host from infection. Also plays an important role in neutrophil activation. Released in response to an inflammatory stimulus, exerts its effect by binding to the G-protein-coupled receptors CXCR1 and CXCR2, primarily found in neutrophils, monocytes and endothelial cells.
Antigen Details
Immunogen
A synthesized peptide: human IL 8
Antigen Species
Human
Gene Name
CXCL8
Gene ID
Protein Name
Interleukin-8
Uniprot ID
Function
IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus. IL-8(6-77) has a 5-10-fold higher activity on neutrophil activation, IL-8(5-77) has increased activity on neutrophil activation and IL-8(7-77) has a higher affinity to receptors CXCR1 and CXCR2 as compared to IL-8(1-77), respectively.
Chemical Properties
Molecular WeightTheoretical: 11 kDa. Actual: 11 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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