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Anti-CBFb Antibody (2U809)
😃Good
Catalog No. TMAB-03709
Anti-CBFb Antibody (2U809) is a Rabbit antibody targeting CBFb. Anti-CBFb Antibody (2U809) can be used in IHC-P,IHC-Fr,IF.
Anti-CBFb Antibody (2U809)
Anti-CBFb Antibody (2U809)
😃Good
Catalog No. TMAB-03709
Anti-CBFb Antibody (2U809) is a Rabbit antibody targeting CBFb. Anti-CBFb Antibody (2U809) can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $470 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CBFb Antibody (2U809) is a Rabbit antibody targeting CBFb. Anti-CBFb Antibody (2U809) can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 2U809 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Forms the heterodimeric complex core-binding factor (CBF) with RUNX family proteins (RUNX1, RUNX2, and RUNX3). RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. |
| Immunogen | A synthesized peptide: human CBF beta |
| Antigen Species | Human |
| Gene Name | CBFB |
| Gene ID | |
| Protein Name | Core-binding factor subunit beta |
| Uniprot ID | |
| Function | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1. |
| Molecular Weight | Theoretical: 22 kDa. Actual: 22 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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