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HGF Protein, Human, Recombinant V2 is expressed in CHO Cells. The accession number is P14210.

| Pack Size | Price | Availability | Quantity |
|---|
| Biological Activity | ED50 < 10.0 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1.0 × 10^5 units/mg. |
| Description | HGF Protein, Human, Recombinant V2 is expressed in CHO Cells. The accession number is P14210. |
| Species | Human |
| Expression System | CHO Cells |
| Accession Number | P14210 |
| Synonyms | SF,scatter factor),HPTA,HGFB,hepatocyte growth factor (hepapoietin A,Hepatocyte Growth Factor,F-TCFB,F-TCF,DFNB39 |
| Construction | Gln32-Ser728 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Molecular Weight | 88-90 kDa (single chain), 59-61 kDa (alpha chain), 30-34 kDa (beta chain) (Reducing conditions) |
| Endotoxin | < 0.2 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from 0.22 μm filtered solution in PBS. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | Hepatocyte Growth Factor (HGF),also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells. HGF binds to the proto-oncogenic c-Met receptor to activate a tyrosine kinase signaling cascade. It regulates cell growth, motility and morphogenesis, thus it plays a pivotal role in angiogenesis, tumorogenesis and tissue regeneration. |

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