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HGF Protein, Human, Recombinant V2

TargetMol | SPR
Catalog No. TMPY-02327U

HGF Protein, Human, Recombinant V2 is expressed in CHO Cells. The accession number is P14210.

HGF Protein, Human, Recombinant V2

HGF Protein, Human, Recombinant V2

TargetMol | SPR
Catalog No. TMPY-02327U
HGF Protein, Human, Recombinant V2 is expressed in CHO Cells. The accession number is P14210.
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Product Information

Biological Activity
ED50 < 10.0 ng/ml, measured in a cell proliferation assay using 4MBr5 cells, corresponding to a specific activity of > 1.0 × 10^5 units/mg.
Description
HGF Protein, Human, Recombinant V2 is expressed in CHO Cells. The accession number is P14210.
Species
Human
Expression System
CHO Cells
Accession NumberP14210
Synonyms
SF,scatter factor),HPTA,HGFB,hepatocyte growth factor (hepapoietin A,Hepatocyte Growth Factor,F-TCFB,F-TCF,DFNB39
Construction
Gln32-Ser728
Protein Purity
> 95% as determined by SDS-PAGE
Molecular Weight88-90 kDa (single chain), 59-61 kDa (alpha chain), 30-34 kDa (beta chain) (Reducing conditions)
Endotoxin< 0.2 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from 0.22 μm filtered solution in PBS.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Hepatocyte Growth Factor (HGF),also known as hepatopoietin-A and scatter factor, is a pleiotropic mitogen belonging to the peptidase S1 family (plasminogen subfamily). It is produced by mesenchymal cells and acts on epithelial cells, endothelial cells and haemopoietic progenitor cells. HGF binds to the proto-oncogenic c-Met receptor to activate a tyrosine kinase signaling cascade. It regulates cell growth, motility and morphogenesis, thus it plays a pivotal role in angiogenesis, tumorogenesis and tissue regeneration.

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