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Anti-FMR1 Antibody (2S809)

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Catalog No. TMAB-06091 Copy Product Info
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Anti-FMR1 Antibody (2S809) is a Rabbit antibody targeting FMR1. Anti-FMR1 Antibody (2S809) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Anti-FMR1 Antibody
(2S809)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1497-10 days7-10 days
50 μL$2627-10 days7-10 days
100 μL$4717-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FMR1 Antibody (2S809) is a Rabbit antibody targeting FMR1. Anti-FMR1 Antibody (2S809) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
Clone
2S809
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; IF: 1:50-200; FCM: 1μg/Test
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus, nucleolus.
Tissue SpecificityHighest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundMultifunctional polyribosome-associated RNA-binding protein that plays a central role in neuronal development and synaptic plasticity through the regulation of alternative mRNA splicing, mRNA stability, mRNA dendritic transport and postsynaptic local protein synthesis of target mRNAs.
Antigen Details
Immunogen
A synthesized peptide: human FMR1
Antigen Species
Human
Gene Name
FMR1
Gene ID
Protein Name
Synaptic functional regulator FMR1
Uniprot ID
Function
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Chemical Properties
Molecular WeightTheoretical: 71 kDa. Actual: 70-75 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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