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Anti-TMEM43 Antibody (4I40)
😃Good
Catalog No. TMAB-13602
Anti-TMEM43 Antibody (4I40) is a Rabbit antibody targeting TMEM43. Anti-TMEM43 Antibody (4I40) can be used in WB,IHC-P,IHC-Fr,IF.
Anti-TMEM43 Antibody (4I40)
Anti-TMEM43 Antibody (4I40)
😃Good
Catalog No. TMAB-13602
Anti-TMEM43 Antibody (4I40) is a Rabbit antibody targeting TMEM43. Anti-TMEM43 Antibody (4I40) can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TMEM43 Antibody (4I40) is a Rabbit antibody targeting TMEM43. Anti-TMEM43 Antibody (4I40) can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Clone | 4I40 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IF: 1:100-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum. Nucleus inner membrane. Retained in the inner nuclear membrane through interaction with EMD and A-and B-lamins. The N- and C-termini are orientated towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen. |
| Tissue Specificity | Highest expression in placenta. Also found at lower levels in heart, ovary, spleen, small intestine, thymus, prostate and testis. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane.Plays a role in the modulation of innate immune signaling through the cGAS-STING pathway by interacting with RNF26. |
| Immunogen | A synthesized peptide: human TMEM43 |
| Antigen Species | Human |
| Gene Name | TMEM43 |
| Gene ID | |
| Protein Name | Transmembrane protein 43 |
| Uniprot ID | |
| Function | May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane. |
| Molecular Weight | Theoretical: 45 kDa. Actual: 42 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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