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Anti-XRCC1 Antibody (7F574)

Catalog No. TMAB-14218 Copy Product Info
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Anti-XRCC1 Antibody (7F574) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (7F574) can be used in WB,ICC/IF.

Anti-XRCC1 Antibody (7F574)

Copy Product Info
🥰Excellent
Catalog No. TMAB-14218

Anti-XRCC1 Antibody (7F574) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (7F574) can be used in WB,ICC/IF.

Anti-XRCC1 Antibody
(7F574)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-XRCC1 Antibody (7F574) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (7F574) can be used in WB,ICC/IF.
Ig Type
IgG
Clone
7F574
Reactivity
Human,Mouse,Rat
Verified Activity
1. 25 μg total protein per lane of various lysates (see on figure) probed with XRCC1 monoclonal antibody, unconjugated (TMAB-14218) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min.
2. 4% Paraformaldehyde-fixed K562 (H) cell; Triton X-100 at r. T. for 20 min; Antibody incubation with (XRCC1) monoclonal Antibody, unconjugated (TMAB-14218) 1:100, 90 min at 37°C; followed by conjugated Goat Anti-Rabbit IgG antibody (green) at 37°C for 90 min, DAPI (blue) was used to stain the cell nuclei. PBS instead of the primary antibody was used as the blank control.
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Note=Accumulates at sites of DNA damage.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundScaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity.
Antigen Details
Immunogen
A synthesized peptide: human XRCC1
Antigen Species
Human
Gene Name
XRCC1
Gene ID
Protein Name
DNA repair protein XRCC1
Uniprot ID
Function
Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents.
Chemical Properties
Molecular WeightTheoretical: 69 kDa. Actual: 90 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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