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Anti-XRCC1 Antibody (7F574) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (7F574) can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
| Description | Anti-XRCC1 Antibody (7F574) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (7F574) can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Clone | 7F574 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Note=Accumulates at sites of DNA damage. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Scaffold protein involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes. Negatively regulates ADP-ribosyltransferase activity of PARP1 during base-excision repair in order to prevent excessive PARP1 activity. |
| Immunogen | A synthesized peptide: human XRCC1 |
| Antigen Species | Human |
| Gene Name | XRCC1 |
| Gene ID | |
| Protein Name | DNA repair protein XRCC1 |
| Uniprot ID | |
| Function | Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. |
| Molecular Weight | Theoretical: 69 kDa. Actual: 90 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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