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Anti-CLDN1 Antibody (7K221)
😃Good
Catalog No. TMAB-04436
Anti-CLDN1 Antibody (7K221) is a Rabbit antibody targeting CLDN1. Anti-CLDN1 Antibody (7K221) can be used in WB.
Anti-CLDN1 Antibody (7K221)
Anti-CLDN1 Antibody (7K221)
😃Good
Catalog No. TMAB-04436
Anti-CLDN1 Antibody (7K221) is a Rabbit antibody targeting CLDN1. Anti-CLDN1 Antibody (7K221) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $149 | 7-10 days | 7-10 days | |
| 50 μL | $262 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-CLDN1 Antibody (7K221) is a Rabbit antibody targeting CLDN1. Anti-CLDN1 Antibody (7K221) can be used in WB. |
| Ig Type | IgG |
| Clone | 7K221 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell junction, tight junction. Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Widely expressed, with highest levels in liver and kidney. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008] |
| Immunogen | A synthesized peptide: human Claudin 1 |
| Gene Name | CLDN1 |
| Gene ID | |
| Protein Name | Claudin-1 |
| Function | Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. |
| Molecular Weight | Theoretical: 23 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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