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Anti-Bid Antibody (3J128)

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Catalog No. TMAB-03140

Anti-Bid Antibody (3J128) is a Rabbit antibody targeting Bid. Anti-Bid Antibody (3J128) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.

Anti-Bid Antibody (3J128)

Anti-Bid Antibody (3J128)

😃Good
Catalog No. TMAB-03140
Anti-Bid Antibody (3J128) is a Rabbit antibody targeting Bid. Anti-Bid Antibody (3J128) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1497-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Bid Antibody (3J128) is a Rabbit antibody targeting Bid. Anti-Bid Antibody (3J128) can be used in FCM, IF, IHC-Fr, IHC-P, IP, WB.
Ig Type
IgG
Clone
3J128
Reactivity
Human
Application
Recommended Dose
FCM=1:50-100; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; IP=1:20-50; WB=1:500-2000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm (By similarity). Mitochondrion membrane. Note=When uncleaved, it is predominantly cytoplasmic. BH3-interacting domain death agonist p15: Mitochondrion membrane. Note=Translocates to mitochondria as an integral membrane protein. BH3-interacting domain death agonist p13: Mitochondrion membrane. Note=Associated with the mitochondrial membran. Isoform 1: Cytoplasm. Isoform 3: Cytoplasm. Isoform 2: Mitochondrion membrane. Note=A significant proportion of isoform 2 localizes to mitochondria, it may be cleaved constitutively.
Tissue SpecificityIsoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundInduces caspases and apoptosis.Counters the protective effect of BCL2.
Antigen Details
Immunogen
A synthesized peptide: human BID
Antigen Species
Human
Gene Name
BID
Gene ID
Protein Name
BH3-interacting domain death agonist
Uniprot ID
Function
The major proteolytic product p15 BID allows the release of cytochrome c. Isoform 1, isoform 2 and isoform 4 induce ICE-like proteases and apoptosis. Isoform 3 does not induce apoptosis. Counters the protective effect of Bcl-2.
Chemical Properties
Molecular WeightTheoretical: 22 kDa. Actual: 22 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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