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PKM2 Protein, Human, Recombinant (His) V2
(Synonyms: THBP1, TCB, pyruvate kinase, muscle, PKM2, PK3, OIP3, HEL-S-30, CTHBP) Copy Product InfoSynonyms: THBP1, TCB, pyruvate kinase, muscle, PKM2, PK3, OIP3, HEL-S-30, CTHBP
Catalog No. TMPY-04465U Copy Product Info
PKM2 Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P14618.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 μg | $123 | 7-10 days | 7-10 days | |
| 20 μg | $197 | 7-10 days | 7-10 days | |
| 50 μg | $398 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by SDS-PAGE
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| Description | PKM2 Protein, Human, Recombinant (His) V2 is expressed in E. coli. The accession number is P14618. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-6xHis |
| Accession Number | P14618 |
| Construction | Ser2-Pro531 |
| Protein Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 50 mM NaCl, 0.05% Brij-35, 1mM DTT, pH7.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | THBP1, TCB, pyruvate kinase, muscle, PKM2, PK3, OIP3, HEL-S-30, CTHBP |
| Research Background | Pyruvate kinase isoform M2 (PKM2) is a member of the pyruvate kinase (PK) family, a pivotal glycolytic enzyme that is consistently changed during tumorigenesis. PKM2 is expressed in some differentiated tissues, such as lung, fat tissue, retina, and pancreatic islets. As the rate-controlling enzyme in glycolysis, PKM2, has also been found to be expressed in embryonic, proliferating, and tumor cells, and it has been considered to be crucial for the metabolism and growth of tumor cells. Recent studies have shown that PKM2 promotes cell proliferation and suppresses cell apoptosis in various tumors. In addition, it has been reported that the PKM2 knockdown affects the Akt and ERK protein kinases. |
| Molecular Weight | 60.1 kDa (Predicted); 60 kDa (Reducing conditions) |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: PKM2 Protein, Human, Recombinant (His) V2 chemical structure | PKM2 Protein, Human, Recombinant (His) V2 molecular weight
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