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Anti-P73 Antibody (5W979)
😃Good
Catalog No. TMAB-09903
Anti-P73 Antibody (5W979) is a Rabbit antibody targeting P73. Anti-P73 Antibody (5W979) can be used in ICC/IF, IF, IHC-Fr, IHC-P.
Anti-P73 Antibody (5W979)
Anti-P73 Antibody (5W979)
😃Good
Catalog No. TMAB-09903
Anti-P73 Antibody (5W979) is a Rabbit antibody targeting P73. Anti-P73 Antibody (5W979) can be used in ICC/IF, IF, IHC-Fr, IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $472 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-P73 Antibody (5W979) is a Rabbit antibody targeting P73. Anti-P73 Antibody (5W979) can be used in ICC/IF, IF, IHC-Fr, IHC-P. |
| Ig Type | IgG |
| Clone | 5W979 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | ICC/IF=1:50-200; IF=1:50-200; IHC-Fr=1:50-200; IHC-P=1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Note=Accumulates in the nucleus in response to DNA damage. |
| Tissue Specificity | Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. Is an activator of FOXJ1 expression. It is an essential factor for the positive regulation of lung ciliated cell differentiation. |
| Immunogen | A synthesized peptide: human p73 |
| Antigen Species | Human |
| Gene Name | TP73 |
| Gene ID | |
| Protein Name | Tumor protein p73 |
| Uniprot ID | |
| Function | Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. [COFACTOR] Binds 1 zinc ion per subunit |
| Molecular Weight | Theoretical: 70 kDa. Actual: 70 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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