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Anti-PGP9.5 Antibody (4F173)

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Catalog No. TMAB-10252 Copy Product Info
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Anti-PGP9.5 Antibody (4F173) is a Rabbit antibody targeting PGP9.5. Anti-PGP9.5 Antibody (4F173) can be used in IF, IHC-Fr, IHC-P, WB.
Anti-PGP9.5 Antibody
(4F173)
Pack SizePriceUSA StockGlobal StockQuantity
25 μL$1517-10 days7-10 days
50 μL$2627-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PGP9.5 Antibody (4F173) is a Rabbit antibody targeting PGP9.5. Anti-PGP9.5 Antibody (4F173) can be used in IF, IHC-Fr, IHC-P, WB.
Ig Type
IgG
Clone
4F173
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IF=1:200-2000; IHC-Fr=1:200-2000; IHC-P=1:200-2000; WB=1:1000-5000
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Endoplasmic reticulum membrane. About 30% of total UCHL1 is associated with membranes in brain.
Tissue SpecificityFound in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research Backgroundcatalyzes the hydrolysis of ubiquitin carboxy-terminal thiolesters to form ubiquitin and a thiol; may play a role in neuropathic pain [RGD]. Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors. Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients.
Antigen Details
Immunogen
Recombinant Protein: human UCHL1 protein
Antigen Species
Human
Gene Name
UCHL1
Gene ID
Protein Name
Ubiquitin carboxyl-terminal hydrolase isozyme L1
Uniprot ID
Function
Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Chemical Properties
Molecular WeightTheoretical: 25 kDa. Actual: 25 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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