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Anti-14-3-3 sigma Antibody (7Y889)

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Catalog No. TMAB-02086

Anti-14-3-3 sigma Antibody (7Y889) is a Mouse antibody targeting 14-3-3 sigma. Anti-14-3-3 sigma Antibody (7Y889) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-14-3-3 sigma Antibody (7Y889)

Anti-14-3-3 sigma Antibody (7Y889)

😃Good
Catalog No. TMAB-02086
Anti-14-3-3 sigma Antibody (7Y889) is a Mouse antibody targeting 14-3-3 sigma. Anti-14-3-3 sigma Antibody (7Y889) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-14-3-3 sigma Antibody (7Y889) is a Mouse antibody targeting 14-3-3 sigma. Anti-14-3-3 sigma Antibody (7Y889) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG1, Kappa
Clone
7Y889
Reactivity
Human
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:50-100; IHC-Fr: 1:400-800; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesMouse
Subcellular LocalizationCytoplasm. Nucleus. Secreted. May be secreted by a non-classical secretory pathway.
Tissue SpecificityPresent mainly in tissues enriched in stratified squamous keratinizing epithelium.
ConstructionRecombinant Antibody
PurificationProtein G purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human 14-3-3 sigma
Antigen Species
Human
Gene Name
SFN
Gene ID
Protein Name
14-3-3 protein sigma
Uniprot ID
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
p53-regulated inhibitor of G2/M progression.
Chemical Properties
Molecular WeightTheoretical: 28 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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