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Anti-AAT Antibody (3D777)
😃Good
Catalog No. TMAB-02133
Anti-AAT Antibody (3D777) is a Rabbit antibody targeting AAT. Anti-AAT Antibody (3D777) can be used in WB,ICC/IF,IP.
Anti-AAT Antibody (3D777)
Anti-AAT Antibody (3D777)
😃Good
Catalog No. TMAB-02133
Anti-AAT Antibody (3D777) is a Rabbit antibody targeting AAT. Anti-AAT Antibody (3D777) can be used in WB,ICC/IF,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $148 | 7-10 days | 7-10 days | |
| 50 μL | $261 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-AAT Antibody (3D777) is a Rabbit antibody targeting AAT. Anti-AAT Antibody (3D777) can be used in WB,ICC/IF,IP. |
| Ig Type | IgG |
| Clone | 3D777 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200; IP: 1:20-50 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Short peptide from AAT: Secreted, extracellular space, extracellular matrix. |
| Tissue Specificity | Plasma. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| Research Background | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. |
| Immunogen | A synthesized peptide: human SERPINA1 |
| Antigen Species | Human |
| Gene Name | SERPINA1 |
| Gene ID | |
| Protein Name | alpha-1-antitrypsin |
| Uniprot ID | |
| Function | Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Short peptide from AAT (SPAAT) is a reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE). |
| Molecular Weight | Theoretical: 47 kDa. Actual: 51 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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