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Anti-KDM5A Antibody (3J281)

😃Good
Catalog No. TMAB-07979

Anti-KDM5A Antibody (3J281) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (3J281) can be used in WB,ICC/IF,IP,FCM.

Anti-KDM5A Antibody (3J281)

Anti-KDM5A Antibody (3J281)

😃Good
Catalog No. TMAB-07979
Anti-KDM5A Antibody (3J281) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (3J281) can be used in WB,ICC/IF,IP,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1487-10 days7-10 days
50 μL$2637-10 days7-10 days
100 μL$4727-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-KDM5A Antibody (3J281) is a Rabbit antibody targeting KDM5A. Anti-KDM5A Antibody (3J281) can be used in WB,ICC/IF,IP,FCM.
Ig Type
IgG
Clone
3J281
Reactivity
Human (predicted:Mouse)
Application
Recommended Dose
WB: 1:500-2000; ICC/IF: 1:50-200; IP: 1:20-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus > nucleolus. Occupies promoters of genes involved in RNA metabolism and mitochondrial function.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
Research BackgroundHistone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'.
Antigen Details
Immunogen
A synthesized peptide: human KDM5A
Antigen Species
Human
Gene Name
KDM5A
Gene ID
Protein Name
Lysine-specific demethylase 5A
Uniprot ID
Function
Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May stimulate transcription mediated by nuclear receptors. May be involved in transcriptional regulation of Hox proteins during cell differentiation. May participate in transcriptional repression of cytokines such as CXCL12.
Chemical Properties
Molecular WeightTheoretical: 192 kDa. Actual: 192 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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