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Anti-GP1BA Antibody (1V805)

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Catalog No. TMAB-06648

Anti-GP1BA Antibody (1V805) is a Rabbit antibody targeting GP1BA. Anti-GP1BA Antibody (1V805) can be used in WB,IHC-P,IHC-Fr,IF.

Anti-GP1BA Antibody (1V805)

Anti-GP1BA Antibody (1V805)

😃Good
Catalog No. TMAB-06648
Anti-GP1BA Antibody (1V805) is a Rabbit antibody targeting GP1BA. Anti-GP1BA Antibody (1V805) can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 μL$1517-10 days7-10 days
50 μL$2617-10 days7-10 days
100 μL$4717-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GP1BA Antibody (1V805) is a Rabbit antibody targeting GP1BA. Anti-GP1BA Antibody (1V805) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Clone
1V805
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionRecombinant Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundGlycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Several polymorphisms and mutations have been described in this gene, some of which are the cause of Bernard-Soulier syndromes and platelet-type von Willebrand disease. [provided by RefSeq, Mar 2010].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GP1BA/CD42b
Antigen Species
Human
Gene Name
GP1BA
Gene ID
Protein Name
Platelet glycoprotein Ib alpha chain
Uniprot ID
Function
GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
Chemical Properties
Molecular WeightTheoretical: 67 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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