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Anti-SCIN Antibody (4Y852)
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Catalog No. TMAH-01073
Anti-SCIN Antibody (4Y852) is an antibody targeting SCIN. Anti-SCIN Antibody (4Y852) can be used in ELISA,IHC.
Anti-SCIN Antibody (4Y852)
Anti-SCIN Antibody (4Y852)
😃Good
Catalog No. TMAH-01073
Anti-SCIN Antibody (4Y852) is an antibody targeting SCIN. Anti-SCIN Antibody (4Y852) can be used in ELISA,IHC.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SCIN Antibody (4Y852) is an antibody targeting SCIN. Anti-SCIN Antibody (4Y852) can be used in ELISA,IHC. |
| Ig Type | Rabbit IgG |
| Clone | 4Y852 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-01073 diluted at 1:100 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm, cytoskeleton. Cell projection, podosome. |
| Tissue Specificity | Expressed in megakaryocytes. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Ca(2+)-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2). In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts. Regulates chondrocyte proliferation and differentiation. Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human SCIN |
| Antigen Species | Human |
| Gene Name | SCIN |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Signal transduction |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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