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Synonyms: TMPY-01650, SMDP-5, SMDP5, SMDP 5, IL5RB, IL3RB, granulocyte-macrophage, colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), CDw131, CD-131, CD131, CD 131


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 10 µg | $113 | 7-10 days | 7-10 days | |
| 20 µg | $175 | 7-10 days | 7-10 days | |
| 50 µg | $316 | 7-10 days | 7-10 days | |
| 100 µg | $490 | 7-10 days | 7-10 days | |
| 200 µg | $793 | 7-10 days | 7-10 days | |
| 500 µg | $1,470 | 7-10 days | 7-10 days |
| Bioactivity | Human IL-3 R Beta, hFc Tag captured on CM5 Chip via Protein A can bind Human GM-CSF, No Tag with an affinity constant of 6.78 μM as determined in SPR assay (Biacore T200) (QC Test). |
| Description | CD131 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is P32927-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc (IgG1) |
| Accession Number | P32927-1 |
| Construction | Thr17-Trp443 |
| Protein Purity | > 95% as determined by Bis-Tris PAGE; > 90% as determined by HPLC |
| Endotoxin | < 1 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | TMPY-01650, SMDP-5, SMDP5, SMDP 5, IL5RB, IL3RB, granulocyte-macrophage, colony stimulating factor 2 receptor, β, low-affinity (granulocyte-macrophage), colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage), CDw131, CD-131, CD131, CD 131 |
| Research Background | Interleukin-3 receptor (IL-3R) is a heterodimer that comprises an IL-3 specific alpha chain (IL-3R alpha) and a common beta chain (beta C) that is shared with the receptors for granulocyte-macrophage colony-stimulating factor (GM-CSF) and IL-5. The beta c subunit does not bind any cytokine by itself but is involved in the formation of high-affinity functional receptors for IL-5 and GM-CSF. These receptors belong to the cytokine receptor superfamily, but they are structurally and functionally more related to each other and thus make up a distinct subfamily. |
| Molecular Weight | 74.63 kDa (Predicted); 75-90 kDa (Reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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