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Anti-Glutaminase Antibody (1D890)
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Catalog No. TMAB-06556
Anti-Glutaminase Antibody (1D890) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (1D890) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
Anti-Glutaminase Antibody (1D890)
Anti-Glutaminase Antibody (1D890)
😃Good
Catalog No. TMAB-06556
Anti-Glutaminase Antibody (1D890) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (1D890) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 μL | $150 | 7-10 days | 7-10 days | |
| 50 μL | $263 | 7-10 days | 7-10 days | |
| 100 μL | $471 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Glutaminase Antibody (1D890) is a Rabbit antibody targeting Glutaminase. Anti-Glutaminase Antibody (1D890) can be used in FCM, ICC/IF, IF, IHC-Fr, IHC-P, WB. |
| Ig Type | IgG |
| Clone | 1D890 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | FCM=1 μg/Test; ICC/IF=1:100-200; IF=1:200-500; IHC-Fr=1:200-500; IHC-P=1:200-500; WB=1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cytoplasm, cytosol. Isoform 3: Mitochondrion. |
| Tissue Specificity | Isoform 1 and isoform 3 are detected in brain cortex. Isoform 3 is highly expressed in astrocytoma, ganglioglioma and ependymoma. Isoform 1 is highly expressed in brain and kidney, but not detected in liver. Isoform 3 is highly expressed in heart and pancreas, detected at lower levels in placenta, lung, pancreas and kidney, but is not detected in liver. Isoform 2 is expressed in cardiac and skeletal muscle. |
| Construction | Recombinant Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]. |
| Immunogen | A synthesized peptide: human GLS |
| Antigen Species | Human |
| Gene Name | GLS |
| Gene ID | |
| Protein Name | Glutaminase kidney isoform, mitochondrial |
| Uniprot ID | |
| Function | Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. |
| Molecular Weight | Theoretical: 73 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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